Brian Setzer Says Autoimmune Disease Left Him Unable to Play Guitar

Veteran rockabilly musician Brian Setzer has revealed he’s currently unable to play guitar, with an unspecified autoimmune disease halting his celebrated abilities.

Setzer shared the news on social media on Thursday (Feb. 13), giving fans an update as to his current status following a few months away from the stage. In his post, he revealed that towards the end of the Stray Cats’ 2024 summer tour (which wrapped in August), he was left with cramping hands and a diminished ability to play guitar.

“I’ve since discovered that I have an auto-immune disease. I cannot play guitar,” he told his followers. “There is no pain, but it feels like I am wearing a pair of gloves when I try to play. I have seen some progress in that I can hold a pen and tie my shoes. I know this sounds ridiculous, but I was at a point where I couldn’t even do that. 

“Luckily, I have the best hospital in the world down the block from me. It’s called the Mayo Clinic. I know I will beat this, it will just take some time.”

Setzer first rose to fame at the start of the ‘80s as the guitarist and vocalist of New York rockabilly outfit Stray Cats. Following a string of successful albums and singles (including Hot 100 top ten hits “Rock This Town” and “Stray Cat Strut” from their 1981 self-titled debut), the group split in 1984 before reforming two years later.

Alongside further splits and reunions, Setzer has also been the leader of the eponymous Brian Setzer Orchestra since 1990. His most recent solo album, The Devil Always Collects, arrived in 2023, while Stray Cats returned in 2019 with 40, their first studio album in 26 years.

Setzer’s battle with an auto-immune disease isn’t the first time the acclaimed musician’s health has kept him away from the stage. In 2019, he was forced to cancel 26 dates of his Christmas Rocks! Tour due to being diagnosed with a severe case of tinnitus – a condition that causes sufferers to hear a constant noise or ringing in their ears.

“I’m truly sorry for the inconvenience this has caused all of the amazing people who make my tour happen and to my unbelievably loyal and devoted fans,” Setzer wrote at the time. “I hate to let you down and I hope you’ll understand.”

Though no touring plans have been affected by Setzer’s recent diagnosis, his positive demeanor bodes well for a swift return to the stage.